Glycomics, One of the 10 emerging technologies that will change the world.

MIT said the field of Glycomics, is “One of the 10 emerging technologies that will change the

world.” Notice, they did not say, one of the 10 medical technologies but one out of ALL

technologies that will change our world. It is as important as DNA and the Genome because the

8 major fundamentals of Glycobiology control both DNA and RNA. We even have the

Glyconome! Glycobiology controls our hormones and how they function…If you cannot get

enough of these 8 essentials life sustaining Glyconutrient’s, no matter how much HGH you take

it will have no effect or a neg. effect I am one of the few true experts in this exploding field. The

value to this more ramped up scientific language is so unique in this article that Google will

get in on these words I am using, KEY in on them and our standing in Google will go up

and up because no other competitor knows the scientific language of this anti-aging

breakthrough.. but Google’s algorithm’s and scrubbers places a very high value when you

write what others cannot or have not. When it is singular, as mine is and only on our

website blog Google loves that! That is why I want to write several articles on this topic so

germane to regeneration and living heathier for much longer. AND, there is big money in

this field selling sugars that heal. Please let me know what you think.

HELP DEFEAT ILLNESS AND GREATLY EXTEND YOU’RE LIFESPAN

Seminal Research by Larry Sosna N.D. PhD HHP

GLYCOBIOLOGY OF LIFE

See and hear what the true great university scientists are saying. “This is the future

today”, declares Dr. Gerald Hart of John Hopkins University…The number one rated

medical/scientific teaching hospital in the entire USA. “We won’t understand

Immunology, Neurology, Developmental Biology or Pathology until we get a handle on

Glycobiology.” ….. “If you ask, what is the Glycome for a single cell type it will be many

thousands of times more complex than the genetic Genome,” says Ajit Varki past

director of the Glycobiology Research and Training Center at Cal Tech. Professor

Raymond Dwek, head of the University of Oxford’s Glycobiology Institute, who

coined the term Glycobiology in 1988 says, “ As recent advances in genetics have

unfolded, the importance of sugars which heal has become ever more apparent.”…..

Varki said, “It’s like we just discovered the continent of North America. Now we have to

send out scouting parties to find out how big it is…..”

New Scientist Magazine, October 2002

I’m certain you have been told many times, sugar is one of the main enemies in life

causing all kinds of disease states and folks that can indeed be true. There are harmful

sugars and there are sugars so vitally important to vigorous good health that without

them we would all have suffered and died a long time ago. In fact, without these

miraculous special sugars we never would have made it out of infancy.

Glyco means sweet, there are bad sugars and ones we cannot live without, they are the

healthy Glyconutrients. If you are on one of those fad diets that does not allow the life

enhancing complex carbohydrates then you cannot make Glycoproteins which are

molecules that combine sugars with proteins as well as glycolipids, which are

combinations of healing complex sugars with fats. The term for these life giving

combinations are called glycoconjugates. These glycoconjugates have brought together

the world’s most brilliant medical scientists to comprehend a field so sophisticated the

combinations of glycoconjugates are infinite in how they arrange themselves to yield a

healthy body free from disease if you have them in high enough blood levels.

It will be useful to provide one with a high level of education concerning the immense

healing powers of a strong personal Glycobiology. Let’s shine some light on what

healthy levels of Glycoconjugates can do for the human body to improve both structure

and function.

Immune System Modulation:

Glyconutrients are necessary for healthy immune cells and a body wide capable

immune system function. They have been shown to:

Play a key role in many aspects of cell and tissue regeneration and repair, as well as

cell survival. They have strong positive effects on asthma and allergies in general.

Glyconutrients are one of the very few methods of preventing and or slowing down even

rheumatoid arthritis, lupus, and improves the symptoms of periodontal disease, canker

sores and herpes simplex 1 of the lips.

They have a favorable outcome in suppressing skin reactions and contact dermatitis as

well as inhibiting bronchitis. Many studies show they can prevent arthritis, substantially

reducing pain and increasing joint mobility in osteoarthritis, the most common form of

arthritis.

CANCER RESEARCH:

Glyconutrients and glycoconjugates help to inhibit growth and or tumor cell metastasis

in certain types of cancer. They do this by instructing white blood cells called Natural

Killer Cells to mobilize and seek out and destroy cancer cells. Today there is an entire

field of Glycobiology devoted to cancer research and the NIH and CDC have received

hundreds of millions in government funds to further enhance the field of Glycobiology

and cancer control.

Stress

An adequate supply of dietary glyconutritional healing sugars is vitally important during

periods of body wide stress, since glycoconjugates synthesized from eight key sugars

play key roles in many aspects of tissue healing and repair as well as cell survival

during extremely stressful periods. Corticotropin-releasing factor receptor is hormone

glycoprotein that regulates responses to emotional and other types of stress by

coordinating the endocrine, behavioral and immune responses to stress through

hormonal actions in the brain.

The Heart and Glycobiology

Glycolipid Conjugates are responsible for correct Low Density Lipid receptor site

instruction…These Low Density Lipids are the kind of cholesterol that can cause a

blocked artery and thus a heart attack…. But regulation of the dreaded LDL’s by

Glycolipid Conjugation makes the likelihood of artery blockage by LDL’s a very unlikely

event.

Most of us have heard that cold water fish oil is protective to the arteries of the heart.

When we all have high levels of Glycolipids the Omega 3 fatty acids become like a

super biological Teflon…coating the linings of the arteries so the bad types of LDL

cholesterol cannot aggregate and build up on the artery linings from both sides of the

coronary arteries thus in the scientific review of many research cardiologists who have

researched Glycolipid conjugation they have published findings that are very highly

suggestive that proper amounts of Glycolipids in the blood protects against a buildup of

bad LDL aggregation, such that the arteries seem to be fully protected from a heart

attack. The problem is a mass of Americans do not have adequate blood levels of

Glycolipid Conjugates especially, Galactose which is of great importance for normal

heart and brain health.

Glyconutritional high levels of galactose, mannose, galactosamine and sialic acid binds

vitamin B12 to make B12 bioavailable to the cells. In other without the above mentioned

healing sugar combinations you can inject all the B12 in the world and it will not work.

The same combination of Glucoconjugates helps people from drug and alcohol cravings

all of which are injurious to the heart and liver.

AND the exact same above described combination, seriously reduces HUNGER

Hormone Function

Gonadotropin hormones are glycoproteins derived from the pituitary gland which

controls the release of many other hormones throughout the body including human

growth hormone (hgh).

Glycosylation of gonadotrophin hormones affects their size, circulatory life span, ease

of movement through cells, storage and secretion, clearance, immunoreactivity and

hormone bioactivity within the entire human body.

Glycosylation of IGF receptors contributes to their tissue regeneration and tissue

differences, which affects their biological activity. If an individual does not have

adequate blood levels of Glycoconjugates (the healing 8 combined sugars) all hormone

activity no matter how much one takes will be seriously insufficient to do their job in the

human body and that can be a health crisis.

Glycoconjugation which does not occur in its proper sequence will lead to a disruption

of insulin formation and correct synthesis and can be causal in some types of diabetes.

The sugars I am about to share with you are so incredible they actually have a

language all of their own. I call them the great hidden code of human life itself. They are

every bit as important as DNA. Amazingly, when these life giving sugars are combined

they can even change mistakes in DNA expression. Mistakes… that can lead to cancer

and every other nightmare type of nightmare illness. However, I am going to show you

how to take a true and certain quantum leap in your ability to regenerate, fight off

virtually all illness, protecting you’re cells, tissues and all of the organs, collectively in all

of our bodies.

You may be thinking this is absurd, sugar is bad for us, correct? Not so simple, just the

sugar D-Ribose is so vital to life that without it we cannot make Messenger RNA and

without messenger RNA you may as well not even make DNA because both are

needed for correct structure and proper functioning of each and every cell, tissue and

organ our bodies. You might even remember from high school biology in the 9th grade

that RNA stands for Ribo Nucleic Acid…and it’s very back bone comes from our good

friend, the amazing D-Ribose SUGAR.

I am very excited to share this science with you. Unfortunately this is a science within

the medical field that is so complex it was not until the 1960’s to 1980’s that we got our

arms around this field of Molecular Glyco-Synthesis. And just like the field of DNA it took

the most brilliant hand full of scientists in molecular bio-science to advance this new

field and show how massively important it is. The field is so important to every phase of

our life cycle; I still study it weekly even though it has been a 20 years endeavor. That is

how important this field is and it is an honor to share this life enhancing information with

you, our family of friends here at AAI …. Though the field to this day is not being brought

to the public with much attention or consistency.

We have given you a small taste of the importance of the 5 carbon sugar D-Ribose now

let’s really delve into the Art and Science of the other life giving sugars.

There are eight Essential Sugars called Saccharides required for Glycoprotein

Synthesis…They are as follows Xylose, Fucose, Mannose, Galactose, Glucose, N-

Acetylglucosamine, N-Acetylgalactosamine, and N-Acetylineuraminic Acid.

What does this mean? It means no expression of protein’s abilities to build up the cells

into tissues and then into organs can occur. No Protein, no big muscles no matter how

hard you work. Actually, no protein , means death That means that without these eight

amazing sugars which create Glycoprotein Synthesis we would not have a body to even

take care of. That is why you must learn how to obtain these super regenerative eight

sugars…if you want to be in a perfected state of excellent health.

Guess what else? We cannot make any HORMONES or even utilize them efficiently

without these super eight sugars but wait there is more good news. Since the early

1990’s Gluco-Scientists found 200 other super sugars from plant based sources,

funding to scientifically evaluate all 200 found so far has several years ago reached the

many hundreds of millions of dollars so are discovering the roles of all 200 sugars.

Mother Nature’s vast array of biochemistry, including these 200 sugars has a specific

purpose. The overwhelming majority of them will be to create an even more complex

language to further healing, cell regeneration and repair. So please don’t be stuck on

eating (sucrose white ultra-refined table sugar) as sucrose in that form is BAD for

human consumption.

Speaking of Hormones, about 10 years ago I learned from Dr. David Wesser M.D.

DDS, a very close friend and teacher, taught if you combine a significant dose of D-

Ribose with Galactose, the human body will regenerate all hormones that have reached

the end of their life cycle, bringing them right back to the top of their life cycle. If you

want to feel like a Greek God, put this into you’re program.

Remember the eight super sugars are a code containing an extensive language. Each

sugar is like a 1000 page book in terms of its ability to communicate instructions

throughout the entire body. Each page in any of the eight books can code and give

hundreds of millions of directions throughout the body. So, we are talking about a code

of life capable of issuing Trillions of life enhancing instructions from the molecular level

to the cells, tissues and organs and even the brain itself gets its instructions to develop

into a brain, as well as sustain you’re brain.

For Illustrative purposes, these molecular communication codes are like precisely

shaped words that protrude from the cells surface and are recognized and understood

by neighboring cells, we call this Glycoform Cellular Communication. It is these eight

amazing Glycoforms that determine your blood type. Imagine that, a sugar

molecule called a Glycoform, N-Acetylgalactosamine will make your blood type A … and

type B blood types are determined by the sugar Galactose. How IMPORTANT are these

eight sugars? You cannot make blood without them, need I say more. Yes indeed there

is so much more but to go further I would need to speak in the language of advanced

biochemistry.

The important factor really is on a practical level which asks the question where do I get

these eight super regenerative sugars? Simply call us at AAI and you can learn how to

obtain the Super Eight!

Mechanisms of the Sialidase and Trans-sialidase Activities of Bacterial Sialyltransferases from

Glycosyltransferase Family 80 (GT80).

Mehr K, Withers SG.

Glycobiology. 2015 Nov 17. pii: cwv105. [Epub ahead of print]

PMID:

 

Similar articles

Select item 265786732.

Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against

Adherent-Invasive Escherichia coli Bacteria Associated with Crohn’s Disease.

Sivignon A, Yan X, Alvarez Dorta D, Bonnet R, Bouckaert J, Fleury E, Bernard J, Gouin SG,

Darfeuille-Michaud A, Barnich N.

MBio. 2015 Nov 17;6(6). pii: e01298-15. doi: 10.1128/mBio.01298-15.

PMID:

 

26582604

26578673

Free Article

Similar articles

Select item 265692243.

Identification of Arsenic Direct-Binding Proteins in Acute Promyelocytic Leukaemia Cells.

Zhang T, Lu H, Li W, Hu R, Chen Z.

Int J Mol Sci. 2015 Nov 10;16(11):26871-26879.

PMID:

 

Select item 265625464.

Comparative study of structural models of Leishmania donovani and human GDP-mannose

pyrophosphorylases.

Daligaux P, Bernadat G, Tran L, Cavé C, Loiseau PM, Pomel S, Ha-Duong T.

Eur J Med Chem. 2015 Oct 30;107:109-118. doi: 10.1016/j.ejmech.2015.10.037. [Epub ahead of print]

PMID:

 

Select item 265585155.

Synthesis of di- and tri-saccharide fragments of Salmonella typhi Vi capsular polysaccharide

and their zwitterionic analogues.

Fusari M, Fallarini S, Lombardi G, Lay L.

Bioorg Med Chem. 2015 Oct 30. pii: S0968-0896(15)30121-8. doi: 10.1016/j.bmc.2015.10.043. [Epub ahead of print]

PMID:

 

Select item 265540936.

Imaging. RNA catch and release.

Larochelle S.

Nat Methods. 2015 Sep;12(9):813. No abstract available.

PMID:

 

Select item 265532867.

Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by

glycoclusters in the natural tissue context.

André S, Kaltner H, Kayser K, Murphy PV, Gabius HJ.

Histochem Cell Biol. 2015 Nov 9. [Epub ahead of print]

PMID:

 

26569224

26562546

26558515

26554093

26553286

Select item 265432578.

Synthesis of cholesteryl-α-D-lactoside via generation and trapping of a stable β-lactosyl iodide.

Davis RA, Fettinger JC, Gervay-Hague J.

Tetrahedron Lett. 2015 Jun 3;56(23):3690-3694. Epub 2015 May 8.

PMID:

 

Select item 265419749.

Enhanced Cross-Linking of Diazirine-Modified Sialylated Glycoproteins Enabled through

Profiling of Sialidase Specificities.

McCombs JE, Zou C, Parker RB, Cairo CW, Kohler JJ.

ACS Chem Biol. 2015 Nov 16. [Epub ahead of print]

PMID:

 

Select item 2653133610.

Glycoconjugates distribution during developing mouse Spinal Cord motor organizer.

Fazel A, Vojoudi E, Ebrahimi V, Ebrahimzadeh A.

Int J Dev Neurosci. 2015 Dec;47(Pt A):2-3. doi: 10.1016/j.ijdevneu.2015.04.016. No abstract available.

PMID:

 

Select item 2652635411.

Identification and functional analysis of two Golgi-localized UDP-galactofuranose

transporters with overlapping functions in Aspergillus niger.

Park J, Tefsen B, Heemskerk MJ, Lagendijk EL, van den Hondel CA, van Die I, Ram

AF.

BMC Microbiol. 2015 Nov 2;15(1):253. doi: 10.1186/s12866-015-0541-2.

PMID:

 

Select item 2652540212.

Candida albicans β-1,2-mannosyltransferase Bmt3 prompts the elongation of the cell-

wall phosphopeptidomannan.

Sfihi-Loualia G, Hurtaux T, Fabre E, Fradin C, Mée A, Pourcelot M, Maes E, Bouckaert

J, Mallet JM, Poulain D, Delplace F, Guérardel Y.

Glycobiology. 2015 Nov 1. pii: cwv094. [Epub ahead of print]

PMID:

 

Select item 2652448113.

26543257

26541974

26526354

26525402

Taming the Reactivity of Glycosyl Iodides To Achieve Stereoselective Glycosidation.

Gervay-Hague J.

Acc Chem Res. 2015 Nov 2. [Epub ahead of print]

PMID:

 

26524481

 

15.

HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study.

Haase CL, Tybjærg-Hansen A, Nordestgaard BG, Frikke-Schmidt R.

Diabetes. 2015 Sep;64(9):3328-33. doi: 10.2337/db14-1603. Epub 2015 May 13.

PMID:

 

25972569

Similar articles

Select item 2596831216.

Glypican4 promotes cardiac specification and differentiation by attenuating canonical

Wnt and Bmp signaling.

Strate I, Tessadori F, Bakkers J.

Development. 2015 May 15;142(10):1767-76. doi: 10.1242/dev.113894.

PMID:

 

25968312

Free Article

Similar articles

Select item 2596449417.

Glucocorticoid-induced leucine zipper: a critical factor in macrophage endotoxin

tolerance.

Hoppstädter J, Kessler SM, Bruscoli S, Huwer H, Riccardi C, Kiemer AK.

J Immunol. 2015 Jun 15;194(12):6057-67. doi: 10.4049/jimmunol.1403207. Epub 2015 May 11.

PMID:

 

25964494

Similar articles

Select item 2596420918.

Tamoxifen regulation of sphingolipid metabolism–Therapeutic implications.

Morad SA, Cabot MC.

Biochim Biophys Acta. 2015 Sep;1851(9):1134-45. doi: 10.1016/j.bbalip.2015.05.001. Epub 2015 May 9. Review.

PMID:

 

25964209

Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-

product signaling in a ceramide-dependent manner.

Nelson MB, Swensen AC, Winden DR, Bodine JS, Bikman BT, Reynolds PR.

m J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H63-9. doi: 10.1152/ajpheart.00043.2015. Epub 2015 Ma

Internalization and accumulation in dendritic cells of a small pH-activatable glycomimetic

fluorescent probe as revealed by spectral detection.

Arsov Z, Švajger U, Mravljak J, Pajk S, Kotar A, Urbančič I, Štrancar J, Anderluh M.

Chembiochem. 2015 Oct 30. doi: 10.1002/cbic.201500376. [Epub ahead of print]

PMID:

 

26515511

Highly Substituted Cyclopentane-CMP Conjugates as Potent Sialyltransferase Inhibitors.

Li W, Niu Y, Xiong DC, Cao X, Ye XS.

J Med Chem. 2015 Oct 22;58(20):7972-90. doi: 10.1021/acs.jmedchem.5b01181. Epub 2015 Oct 7.

PMID:

 

26406919

Activation and function of murine primary microglia in the absence of the prion protein.

Pinheiro LP, Linden R, Mariante RM.

J Neuroimmunol. 2015 Sep 15;286:25-32. doi: 10.1016/j.jneuroim.2015.07.002. Epub 2015 Jul 10.

PMID:

 

26298321

Phospholipase D2 drives mortality in sepsis by inhibiting neutrophil extracellular trap formation

and down-regulating CXCR2.

Lee SK, Kim SD, Kook M, Lee HY, Ghim J, Choi Y, Zabel BA, Ryu SH, Bae YS.

J Exp Med. 2015 Aug 24;212(9):1381-90. doi: 10.1084/jem.20141813. Epub 2015 Aug 17.

PMID:

 

26282875

Activation of human naïve Th cells increases surface expression of GD3 and induces

neoexpression of GD2 that colocalize with TCR clusters.

Villanueva-Cabello TM, Mollicone R, Cruz-Muñoz ME, López-Guerrero DV, Martínez-Duncker I.

Glycobiology. 2015 Dec;25(12):1454-64. doi: 10.1093/glycob/cwv062. Epub 2015 Aug 11.

PMID:

 

26263924

[CONTEMPORARY CONCEPTION OF IMMUNE RESPONSE ACTIVATION MECHA- NISM BY

CONJUGATED POLYSACCHARIDE VACCINES].

Kolesnikov AV, Kozyr AV, Schemyakin IG, Dyatlov IA.

Zh Mikrobiol Epidemiol Immunobiol. 2015 May-Jun;(3):97-106. Review. Russian.

PMID:

 

26259279

[The significance of fucosylated glycoconjugates of human milk in nutrition of newborns and

infants].

Lis-Kuberka J, Orczyk-Pawiłowicz M.

Postepy Hig Med Dosw (Online). 2015 Jul 22;69:811-29. Polish.

PMID:

 

26206995

HUMAN MICROBIOTA. Small molecules from the human microbiota.

Donia MS, Fischbach MA.

Science. 2015 Jul 24;349(6246):1254766. doi: 10.1126/science.1254766. Epub 2015 Jul 23. Review.

PMID:

Temporary Conversion of Protein Amino Groups to Azides: A Synthetic Strategy for

Glycoconjugate Vaccines.

Lipinski T, Bundle DR.

Methods Mol Biol. 2015;1331:145-57. doi: 10.1007/978-1-4939-2874-3_9.

PMID:

 

26169739

Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+

DendriticCells and Induces Upregulation of CD16 and CD1c Expression.

Teirlinck AC, Roestenberg M, Bijker EM, Hoffman SL, Sauerwein RW, Scholzen A.

Infect Immun. 2015 Sep;83(9):3732-9. doi: 10.1128/IAI.00473-15. Epub 2015 Jul 13.

PMID:

 

26169270

Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a

Murine Model.

Amano S, Inagawa H, Nakata Y, Ohmori M, Kohchi C, Soma G.

Anticancer Res. 2015 Aug;35(8):4509-14.

PMID:

 

26168494

Similar articles

Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis.

Park SD, Cheon SY, Park TY, Shin BY, Oh H, Ghosh S, Koo BN, Lee SK.

Biochem Biophys Res Commun. 2015 Aug 28;464(3):711-7. doi: 10.1016/j.bbrc.2015.07.008. Epub 2015 Jul 6.

PMID:

 

26159927

Glycoprotein from street rabies virus BD06 induces early and robust immune responses when

expressed from a non-replicative adenovirus recombinant.

Wang S, Sun C, Zhang S, Zhang X, Liu Y, Wang Y, Zhang F, Wu X, Hu R.

Arch Virol. 2015 Sep;160(9):2315-23. doi: 10.1007/s00705-015-2512-1. Epub 2015 Jul 5.

PMID:

 

26143474

Modulation of proinflammatory NF-κB signaling by ectromelia virus in RAW 264.7 murine

macrophages.

Struzik J, Szulc-Dąbrowska L, Papiernik D, Winnicka A, Niemiałtowski M.

Arch Virol. 2015 Sep;160(9):2301-14. doi: 10.1007/s00705-015-2507-y. Epub 2015 Jul 4.

PMID:

 

26141411